The Constitution is not an instrument for the government to restrain the people, it is an instrument for the people to restrain the government — lest it come to dominate our lives and interests.
Source, in full
As quoted in The Best Liberal Quotes Ever : Why the Left is Right (2004) by William P. Martin. Though widely attributed to Henry, this statement has not been sourced to any document before the 1990s and appears to be at odds with his beliefs as a strong opponent of the adoption of the US Constitution.