The origin of this quote is often misattributed to Cicero; however, it is from Line 135-136 of Book 2, Satire 2 by Horace, "Quocirca vivite fortes, fortiaque adversis opponite pectora rebus." The English translation that most closely matches the one misrepresented as Cicero's is from a collection of Horace's prose written by E. C. Wickham, "So live, my boys, as brave men; and if fortune is adverse, front its blows with brave hearts."
More quotes by Cicero
I never cease urging peace, which, however unfair, is better than the justest war in the world.
Every one is least known to himself, and it is very difficult for a man to know himself.
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In the fields of observation chance favors only the prepared mind.
Some are born great, some achieve greatness, and some have greatness thrust upon 'em.
O Fortune, cruellest of heavenly powers,
Why make such game of this poor life of ours?
Attribution
Quote text and notes from Wikiquote: Cicero (page history), available under CC BY-SA 4.0. Source quality and labels are our own summary of what Wikiquote records.