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Those things, which are experienced to be in their whole nature, or in their most remarkable properties, so contrary to animal life, as in a small quantity to prove destructive to it, are called Poisons: whether they are hurtful by being taken inwardly at the mouth, or communicated to the body externally by a wound.

— Richard Mead A Mechanical Account of Poisons (1702)

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The Viper has always been so remarkable for its venom, that the most remote antiquity made it an emblem of what is hurtful and destructive. Nay, so terrible was the nature of these creatures, that they were very commonly thought to be sent as executioners of divine vengeance upon mankind for enormous crimes, which had escaped the common course of justice.

A Mechanical Account of Poisons (1702)

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