Once the threshold is crossed when there is a self-sustaining level of life in space, then life's long-range future will be secure irrespective of any of the risks on Earth (with the single exception of the catastrophic destruction of space itself).

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Quote text and notes from Wikiquote: Martin Rees (page history), available under CC BY-SA 4.0. Source quality and labels are our own summary of what Wikiquote records.