For extreme diseases, extreme methods of cure, as to restriction, are most suitable.

Extreme remedies are very appropriate for extreme diseases. Compare: "A desperate disease requires a dangerous remedy", Guy Fawkes, in admitting to the Gunpowder Plot; "Diseases desperate grown By desperate appliance are relieved, Or not at all", Shakespeare, Hamlet, Act iv, Sc. 3; "For a desperate disease a desperate cure", Montaigne, The Custom of the Isle of Cea, Ch. iii; Dryden, The Hind and the Panther, Pt. iii, l. 1112