A very similar remark is often attributed to White, but may actually be a paraphrased version of the above statement: "Analyzing humor is like dissecting a frog. Few people are interested and the frog dies of it."
More quotes by E. B. White
Once in everyone's life there is apt to be a period when he is fully awake, instead of half asleep.
I am a member of a party of one, and I live in an age of fear.
Attribution
Quote text and notes from Wikiquote: E. B. White (page history), available under CC BY-SA 4.0. Source quality and labels are our own summary of what Wikiquote records.