Nothing in the world can take the place of persistence. Talent will not; nothing is more common than unsuccessful men with talent. Genius will not; unrewarded genius is almost a proverb. Education will not; the world is full of educated derelicts. Persistence and determination alone are omnipotent. The slogan "press on" has solved and always will solve the problems of the human race.

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Source, in full

Quote from a program at a Coolidge memorial service (1933); cited in The Oxford Dictionary of Quotations (1999). The passage did not originate with Coolidge, but evolved over several decades, appearing as early as 1881 in a youth guidance book. From

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Quote text and notes from Wikiquote: Calvin Coolidge (page history), available under CC BY-SA 4.0. Source quality and labels are our own summary of what Wikiquote records.