In order to seek truth, it is necessary once in the course of our life, to doubt, as far as possible, of all things.

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Notes from Wikiquote

Original Latin: Veritatem inquirenti, semel in vita de omnibus, quantum fieri potest, esse dubitandum

Variants

If you would be a real seeker after truth, you must at least once in your life doubt, as far as possible, all things.

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Quote text and notes from Wikiquote: René Descartes (page history), available under CC BY-SA 4.0. Source quality and labels are our own summary of what Wikiquote records.