The atom can't be seen, yet its existence can be proved. And it is simple to prove that it can't ever be seen. It has to be studied by indirect evidence — and the technical difficulty has been compared to asking a man who has never seen a piano to describe a piano from the sound it would make falling downstairs in the dark.

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Quote text and notes from Wikiquote: Carl David Anderson (page history), available under CC BY-SA 4.0. Source quality and labels are our own summary of what Wikiquote records.