Skip to content

Quotes from The reserve-capacity hypothesis — Bret Weinstein

born 1969 United States

← All quotes by Bret Weinstein

5 quotes

This appears to have greatly elongated the telomeres of laboratory mice.

The reserve-capacity hypothesis (2002)

(6) In iteroparous organisms selection tends to co-ordinate rates of senescence between tissues, such that no one organ generally limits life-span.

The reserve-capacity hypothesis (2002)

(4) With that trade-off as a fundamental constraint, selection adjusts telomere lengths—longer telomeres increasing the capacity for repair, shorter telomeres increasing tumor resistance.

The reserve-capacity hypothesis (2002)

We hypothesize that (1) in vertebrates, a telomeric fail-safe inhibits tumor formation by limiting cellular proliferation. (2) The same system results in the progressive degradation of tissue function with age.

The reserve-capacity hypothesis (2002)

(3) These patterns are manifestations of an evolved antagonistic pleiotropy in which extrinsic causes of mortality favor a species-optimal balance between tumor suppression and tissue repair.

The reserve-capacity hypothesis (2002)

Attribution

Quotes and notes from Wikiquote: Bret Weinstein (page history), available under CC BY-SA 4.0.